Heartburn Research Today is a free monthly online journal that collates and summarizes the latest research about Heartburn, including details on symptoms, causes, prevention, treatment, diet, reflux, drugs.

Fundoplication eliminates chronic cough due to non-acid reflux identified by impedance pH monitoring.

Mainie I, Tutuian R, Agrawal A, Hila A, Highland KB, Adams DB, Castell DO

Division of Gastroenterology and Hepatology, Medical University South Carolina, 96 Jonathan Lucas Street, 210 Clinical Science Building, P O Box 250327 Charleston, SC 29425, USA. mainie@musc.edu

The symptoms of extra-oesophageal gastro-oesophageal reflux disease (GORD) (such as chronic cough and hoarseness) are traditionally more difficult to treat than typical GORD symptoms (heartburn and regurgitation). Patients with extra-oesophageal manifestations may require longer and higher doses of acid suppressive therapy. In patients not responding to acid suppressive therapy the physician faces a dilemma as to whether the symptoms are due to ongoing acid reflux, non-acid reflux, or not associated with reflux. We report the case of a 45 year old woman with a history of a chronic cough referred for fundoplication after documenting her symptoms were associated with non-acid reflux using multichannel intraluminal impedance and pH (MII-pH).

Published 30 May 2005 in Thorax, 60(6): 521-3.
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